See
Biosensors
Engineered proteins that turn a conformational change into a change in fluorescence — read out by FRET, fluorescence lifetime, or single-molecule tracking in living cells.
Decoding dynamic states of living systems.
We build molecular, imaging and computational tools to observe living biology with greater spatial, temporal, molecular and quantitative precision.
What we build
Tools for seeing and steering living cells
We design the proteins, build the microscopes and write the algorithms — so that watching a process and controlling it become the same experiment.
Steer
Optogenetics
Light-controlled switches that recruit a protein to a chosen location, or turn its activity on and off — in seconds, and only where we illuminate.
Observe
Microscopy
Imaging systems built in-house for live, quantitative measurement — single-molecule, light-sheet, fluorescence-lifetime and structured illumination — together with the analysis that turns a recording into numbers.
Design
AI-based protein design
Generative models that propose new sensors, actuators and binders — which we then build and test directly in living cells, closing the loop between design and measurement.
Latest paper
From the lab
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